In-House DNA Engineering Service
Instead of investing time performing your own DNA manipulations, let us do the work for you. We can do any job with low- or high-copy plasmids, BACs, and the E.coli chromosome.
Animal / Mouse model
- Conditional knock-out
e.g. to analyse the function of a gene - Exchange of exons
e.g. to humanize the animal model - Point mutations
e.g. to analyse the effect of SNPs - Reporter fusions
e.g. to analyse the expression pattern of a gene - Promoter fusions
e.g expression of a cDNA from a tissue specific promoter - Fusion proteins
e.g. SNAP-tag for detection, localisation and affinity purification
Modifications of the E.coli chromosome
- Knock-out / interruption of chromosomal genes
- Knock-out / removal of chromosomal genes
- Exchange of chromosomal genes
- Replacement of a chromosomal promoter
You provide the name of the gene to be targeted, we supply the targeting vector according to your specifications. Please contact our DNA Engineering department, at contact@genebridges.com for further information.